Dual-targeting of aberrant glucose metabolism in glioblastoma
نویسندگان
چکیده
منابع مشابه
Dual-targeting of aberrant glucose metabolism in glioblastoma
BACKGROUND Glioblastoma (GBM) is the most common and malignant primary brain tumor. In contrast to some other tumor types, aberrant glucose metabolism is an important component of GBM growth and chemoresistance. Recent studies of human orthotopic GBM in mice and in situ demonstrated GBM cells rely on both glycolysis and mitochondrial oxidation for glucose catabolism. These observations suggest ...
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ژورنال
عنوان ژورنال: Journal of Experimental & Clinical Cancer Research
سال: 2015
ISSN: 1756-9966
DOI: 10.1186/s13046-015-0130-0